Feline Frisky With Cats That Look Like Pin-Up Girls

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Justin Bieber and Selena Gomez call it quits

NEW YORK (AP) — A source confirms to The Associated Press that Justin Bieber is no longer Selena Gomez's "Boyfriend."

The source is not authorized to discuss the split with the press and spoke on condition of anonymity.

The breakup apparently happened last week, and distance and their busy schedules were cited as factors.

The 18-year-old "Boyfriend" singer is touring to promote his latest album, while 20-year-old Gomez is filming a "Wizards of Waverly Place" reunion for the Disney Channel.

The pair first stepped up publicly in February 2011.

E! News was the first to report the split.

Bieber seems to be doing OK, at least publicly. On the red carpet of Wednesday's Victoria's Secret fashion show he said, "I'd rather be here than anywhere in the world."

___

Online:

http://www.justinbiebermusic.com/

http://www.selenagomez.com/

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Malaria vaccine a letdown for infants

LONDON (AP) — An experimental malaria vaccine once thought promising is turning out to be a disappointment, with a new study showing it is only about 30 percent effective at protecting infants from the killer disease.

That is a significant drop from a study last year done in slightly older children, which suggested the vaccine cut the malaria risk by about half — though that is still far below the protection provided from most vaccines. According to details released on Friday, the three-shot regimen reduced malaria cases by about 30 percent in infants aged 6 to 12 weeks, the target age for immunization.

Dr. Jennifer Cohn, a medical coordinator at Doctors Without Borders, described the vaccine's protection levels as "unacceptably low." She was not linked to the study.

Scientists have been working for decades to develop a malaria vaccine, a complicated endeavor since the disease is caused by five different species of parasites. There has never been an effective vaccine against a parasite. Worldwide, there are several dozen malaria vaccine candidates being researched.

In 2006, a group of experts led by the World Health Organization said a malaria vaccine should cut the risk of severe disease and death by at least half and should last longer than one year. Malaria is spread by mosquitoes and kills more than 650,000 people every year, mostly young children and pregnant women in Africa. Without a vaccine, officials have focused on distributing insecticide-treated bed nets, spraying homes with pesticides and ensuring access to good medicines.

In the new study, scientists found babies who got three doses of the vaccine had about 30 percent fewer cases of malaria than those who didn't get immunized. The research included more than 6,500 infants in Africa. Experts also found the vaccine reduced the amount of severe malaria by about 26 percent, up to 14 months after the babies were immunized.

Scientists said they needed to analyze the data further to understand why the vaccine may be working differently in different regions. For example, babies born in areas with high levels of malaria might inherit some antibodies from their mothers which could interfere with any vaccination.

"Maybe we should be thinking of a first-generation vaccine that is targeted only for certain children," said Dr. Salim Abdulla of the Ifakara Health Institute in Tanzania, one of the study investigators.

Results were presented at a conference in South Africa on Friday and released online by the New England Journal of Medicine. The study is scheduled to continue until 2014 and is being paid for by GlaxoSmithKline and the PATH Malaria Vaccine Initiative.

"The results look bad now, but they will probably be worse later," said Adrian Hill of Oxford University, who is developing a competing malaria vaccine. He noted the study showed the Glaxo vaccine lost its potency after several months. Hill said the vaccine might be a hard sell, compared to other vaccines like those for meningitis and pneumococcal disease — which are both effective and cheap.

"If it turns out to have a clear 30 percent efficacy, it is probably not worth it to implement this in Africa on a large scale," said Genton Blaise, a malaria expert at the Swiss Tropical and Public Health Institute in Basel, who also sits on a WHO advisory board.

Eleanor Riley of the London School of Hygiene and Tropical Medicine, said the vaccine might be useful if used together with other strategies, like bed nets. She was involved in an earlier study of the vaccine and had hoped for better results. "We're all a bit frustrated that it has proven so hard to make a malaria vaccine," she said. "The question is how much money are the funders willing to keep throwing at it."

Glaxo first developed the vaccine in 1987 and has invested $300 million in it so far.

WHO said it couldn't comment on the incomplete results and would wait until the trial was finished before drawing any conclusions.

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How 'poor judgment' felled military star Petraeus

WASHINGTON (Reuters) - David Petraeus was a star on the battlefield, commanding the Iraq and Afghanistan wars, but was undone by "poor judgment" in engaging in an extramarital affair that led to his downfall as CIA director.

Just two days after his 60th birthday, Petraeus stepped down from the spy agency where he had held the top office since September 6, 2011.

"After being married for over 37 years, I showed extremely poor judgment by engaging in an extramarital affair. Such behavior is unacceptable, both as a husband and as the leader of an organization such as ours. This afternoon, the President graciously accepted my resignation," Petraeus told the shadow warriors he commanded at CIA.

It was a stunning downfall for a revered military man who was seen as one of the top American leaders of his generation and was once considered a potential contender for the White House.

Petraeus was credited with pulling Iraq from the brink of all-out civil war and for battlefield successes in Afghanistan after overseeing a surge of 30,000 troops ordered by President Barack Obama in late 2009. He became known for counter-insurgency strategies that were seen as gaining ground against the Taliban in Afghanistan.

"I don't think he was professionally overrated. His were genuine accomplishments," said James Carafano, a war historian with the conservative Heritage Foundation think tank.

At the time of his nomination to the CIA post, some Washington insiders had said the White House wanted to find a prominent position for Petraeus to ensure he would not be recruited by Republicans as a challenger to the 2012 Obama-Biden ticket.

When he was nominated to lead the CIA there were some concerns in intelligence circles that the high-profile four-star Army general might not be able to lead from the shadows as appropriate for a spy chief.

But once he took over the head office at the U.S. spy agency, Petraeus kept a decidedly low public profile.

Senate Intelligence Committee Chairman Dianne Feinstein, a Democrat, expressed regret about the resignation of "one of America's best and brightest" and said it was an "enormous loss" for the country.

"At CIA, Director Petraeus gave the agency leadership, stature, prestige and credibility both at home and abroad. On a personal level, I found his command of intelligence issues second to none," she said.

RESIGNATION ACCEPTED

After accepting his resignation about a year-and-a-half after nominating Petraeus to the CIA post, Obama said: "By any measure, he was one of the outstanding General officers of his generation, helping our military adapt to new challenges, and leading our men and women in uniform through a remarkable period of service in Iraq and Afghanistan, where he helped our nation put those wars on a path to a responsible end."

Earlier this week, in a Newsweek article entitled "General David Petraeus's Rules for Living," he listed 12 lessons for leadership. Number 5 was: "We all will make mistakes. The key is to recognize them and admit them, to learn from them, and to take off the rear­ view mirrors - drive on and avoid making them again."

In 2010 Petraeus stepped into the breach as the new commander of U.S. forces in Afghanistan to replace General Stanley McChrystal who was fired by Obama in a scandal over an article in which McChrystal and his aides made mocking comments about the president and some of his top advisers.

In 2009 Petraeus was diagnosed with early-stage prostate cancer and underwent radiation treatment. The media-friendly general joked at that time at a Washington event that reporters were only gathered "to see if the guy is still alive."

Petraeus, born in Cornwall, New York, lives in Virginia with his wife Holly. They have two grown children, a son who was an Army Ranger who served in Afghanistan, and a daughter.

Petraeus's wife, Holly, is an activist and volunteer who champions military families, and she continued that work after her husband retired from the military and moved to the CIA.

She currently is assistant director of the office of servicemember affairs at the Consumer Financial Protection Bureau, where she tries to keep unscrupulous lenders from taking advantage of military personnel. The bureau was championed by Harvard law professor Elizabeth Warren, who was elected to the Senate from Massachusetts this week.

Holly Petraeus is the daughter of four-star General William Knowlton, who was superintendent of the U.S. Military Academy at West Point when Petraeus was a cadet.

She briefed the press at the Pentagon on her efforts recently and was introduced by Defense Secretary Leon Panetta, who called her "a true friend of the Department of Defense and a dedicated member of our military family."

Petraeus has four Defense Distinguished Service Medal awards, three Distinguished Service Medal awards, the Bronze Star Medal for valor, and the State Department Distinguished Service Award.

He has a doctorate in international relations from Princeton University.

(Additional reporting by David Alexander, Matt Spetalnick and Diane Bartz; Editing by Warren Strobel and Jackie Frank)

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Transgender Pakistanis face society's scorn

RAWALPINDI, Pakistan (AP) — Dressed up in elaborate, feminine outfits and artfully applied makeup, they are showered with money while dancing at all-male wedding parties. But the lives of transgender people in Pakistan are also marked by harassment, rejection and poverty.

Transgender people live in a tenuous position in conservative Pakistan, where the roles of the sexes are traditionally starkly drawn. Families often push them out of the home when they're young, forcing many to prostitute themselves to earn a living.

One role where they are tolerated is as dancers at weddings and other celebrations at which men and women are strictly segregated. In between the dancing and showers of rupee notes, they must fend off groping from drunken guests.

"I don't understand why people feel it is their duty to tease and taunt us," said one transgender Pakistani who goes by the name Symbal. Many in the transgender community pick a name for themselves and do not use their last name to protect their family.

Others beg on the streets or earn money by blessing newborn babies. The blessings reflect a widespread belief in Pakistan and other South Asian nations that God answers the prayers of someone who was born underprivileged, said Iqbal Hussain, a Pakistani researcher who has studied the transgender community. But he cautioned that didn't mean people were ready to give them equal rights.

In recent years the community has gained some government protection. A Supreme Court ruling in 2011 allowed them to get national identity cards recognizing them as a separate identity — neither male or female — and allowing them to vote. In neighboring India, the election commission ruled in 2009 that transgender people could register to vote as "other," rather than male or female.

In other parts of the region and Muslim world, the attitude toward transgenders is also complex. In Thailand, the community is very visible and broadly tolerated. Transgender people are regularly seen on TV soap operas, working at department store cosmetics counters or popular restaurants and walking the runways in numerous transgender beauty pageants.

Many transgender Indonesians publicly wear women's clothes and makeup and work as singers. But societal disdain still runs deep. They have taken a much lower profile in recent years, following a series of attacks by Muslim hard-liners.

In Malaysia, Muslim men who wear women's clothes can be prosecuted in Islamic courts.

In the Arab world, there is little opportunity for transgender people to openly show their identity in public. In 2007, Kuwait made "imitating members of the opposite sex" a crime, leading to the arrest of hundreds of transgender women, Human Rights Watch said. In Iraq, extremists have targeted and killed people perceived of being gay or effeminate.

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Roger Waters plays with band of wounded veterans

NEW YORK (AP) — Roger Waters honored wounded veterans in New York by performing with them at the annual Stand Up for Heroes benefit, Thursday night.

The founding member of Pink Floyd took to the stage of the Beacon Theater with 14 wounded soldiers he met recently at the Walter Reed Army Medical Center in Washington, D.C. He rehearsed with them at the hospital, and for the past few days in New York.

The event benefited the Bob Woodruff Foundation, which helps returning veterans and their families, and featured Waters, Bruce Springsteen, Ricky Gervais, Robin Williams, and others.

Before the show, Waters chatted with veterans and called the experience "fantastic." He says he's "looking forward to pulling for the rest of these guys with their comrades" during the healing process.

He says that he shares "enormous empathy with the men."

"I lost my grandfather in 1916 and my father in 1944, so I've been around the sense of loss and what loss from war can do to people," Waters said.

"I never talk about the politics because it's not relevant to me. I'm not interested in it," he said. "What I am interested in is the burdens these guys bear and would never question motive or even dream of talking about any of the politics."

He added: "If any of us have a responsibility in our lives it is to tear down the walls of indifference and miscommunication between ourselves and our fellow men."

Waters said he rehearsed with many of the soldiers at the hospital in between their medical procedures. Before the show, he walked the red carpet with Staff Sgt. Robert Henline, who was not in the band. In 2007, Henline was the sole survivor of a roadside bombing north of Baghdad. As a result, he suffered burns over 38 percent of his body and his head was burned to the skull.

Henline, who fought for his life after the attack, has endured more than 40 surgeries.

Still, he maintains a sense of humor. On the open red carpet on a chilly night, Waters pushed closer to Henline for warmth.

"Get next to the burn guy. I'm good. I'm heated up," Henline joked.

No surprise. The retired soldier says he's been doing stand-up comedy for the past year and a half.

Waters performed three songs with the veterans, including the Pink Floyd classic, "Wish You Were Here."

Waters said he didn't think there would be a reunion with his former band.

"I think David (Gilmour) is retired by and large. I shouldn't speak for him. But that's the impression I get."

Waters then added: "Hey whatever. All good things come to an end."

While his mammoth tour of "The Wall" ended this summer, Waters promised the theatrical version would hit the Broadway stage in the near future.

The Bob Woodruff Foundation has supported more than 1 million veterans, service members, and their families since it began in 2008.

_____

John Carucci covers entertainment for The Associated Press. Follow him at —http://www.twitter.com/jcarucci_ap

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Malaria vaccine a letdown for infants

LONDON (AP) — An experimental malaria vaccine once thought promising is turning out to be a disappointment, with a new study showing it is only about 30 percent effective at protecting infants from the killer disease.

That is a significant drop from a study last year done in slightly older children, which suggested the vaccine cut the malaria risk by about half — though that is still far below the protection provided from most vaccines. According to details released on Friday, the three-shot regimen reduced malaria cases by about 30 percent in infants aged 6 to 12 weeks, the target age for immunization.

Dr. Jennifer Cohn, a medical coordinator at Doctors Without Borders, described the vaccine's protection levels as "unacceptably low." She was not linked to the study.

Scientists have been working for decades to develop a malaria vaccine, a complicated endeavor since the disease is caused by five different species of parasites. There has never been an effective vaccine against a parasite. Worldwide, there are several dozen malaria vaccine candidates being researched.

In 2006, a group of experts led by the World Health Organization said a malaria vaccine should cut the risk of severe disease and death by at least half and should last longer than one year. Malaria is spread by mosquitoes and kills more than 650,000 people every year, mostly young children and pregnant women in Africa. Without a vaccine, officials have focused on distributing insecticide-treated bed nets, spraying homes with pesticides and ensuring access to good medicines.

In the new study, scientists found babies who got three doses of the vaccine had about 30 percent fewer cases of malaria than those who didn't get immunized. The research included more than 6,500 infants in Africa. Experts also found the vaccine reduced the amount of severe malaria by about 26 percent, up to 14 months after the babies were immunized.

Scientists said they needed to analyze the data further to understand why the vaccine may be working differently in different regions. For example, babies born in areas with high levels of malaria might inherit some antibodies from their mothers which could interfere with any vaccination.

"Maybe we should be thinking of a first-generation vaccine that is targeted only for certain children," said Dr. Salim Abdulla of the Ifakara Health Institute in Tanzania, one of the study investigators.

Results were presented at a conference in South Africa on Friday and released online by the New England Journal of Medicine. The study is scheduled to continue until 2014 and is being paid for by GlaxoSmithKline and the PATH Malaria Vaccine Initiative.

"The results look bad now, but they will probably be worse later," said Adrian Hill of Oxford University, who is developing a competing malaria vaccine. He noted the study showed the Glaxo vaccine lost its potency after several months. Hill said the vaccine might be a hard sell, compared to other vaccines like those for meningitis and pneumococcal disease — which are both effective and cheap.

"If it turns out to have a clear 30 percent efficacy, it is probably not worth it to implement this in Africa on a large scale," said Genton Blaise, a malaria expert at the Swiss Tropical and Public Health Institute in Basel, who also sits on a WHO advisory board.

Eleanor Riley of the London School of Hygiene and Tropical Medicine, said the vaccine might be useful if used together with other strategies, like bed nets. She was involved in an earlier study of the vaccine and had hoped for better results. "We're all a bit frustrated that it has proven so hard to make a malaria vaccine," she said. "The question is how much money are the funders willing to keep throwing at it."

Glaxo first developed the vaccine in 1987 and has invested $300 million in it so far.

WHO said it couldn't comment on the incomplete results and would wait until the trial was finished before drawing any conclusions.

___

Online:

www.nejm.org

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'Evolved': Hannity, Boehner say GOP should tackle immigration reform

Sean Hannity (AP)Well, that was fast.

Just two days after President Barack Obama sailed to re-election over Mitt Romney, boosted by more than 70 percent of the Latino vote, some Republicans are striking a new tone on illegal immigration.

Conservative Fox News and radio host Sean Hannity said Thursday that his views on immigration have "evolved." Hannity continued:

We've gotta get rid of the immigration issue altogether. It's simple for me to fix it. I think you control the border first, you create a pathway for those people that are here, you don't say you gotta go home. And that is a position that I've evolved on. Because you know what—it just—it's gotta be resolved. The majority of people here—if some people have criminal records you can send 'em home—but if people are here, law-abiding, participating, four years, their kids are born here ... first secure the border, pathway to citizenship ... then it's done. But you can't let the problem continue. It's gotta stop.

Meanwhile, in an interview with ABC News' Diane Sawyer, House Speaker John Boehner said he is "confident" the two parties can agree to a deal on immigration.

"This issue has been around far too long," Boehner said. "A comprehensive approach is long overdue, and I'm confident that the president, myself, others can find the common ground to take care of this issue once and for all."

Just two years ago, Boehner said it was worth considering amending the U.S. Constitution to end birthright citizenship, because he said it might discourage people from illegally crossing the border.

Former Secretary of State Condoleezza Rice, who supports immigration reform, said on CBS on Friday that Republicans had sent "mixed messages" about immigration. "On the immigration issue, which turned out to be very important, and some issues about women, too, some mixed messages were sent," she said.

The party has been searching for answers about why Mitt Romney lost what seemed like a very winnable election. Many within the party have pointed to the GOP's demographics problem: Romney lost every group except for white voters, which is a shrinking portion of the electorate. Latinos this year made up 10 percent of all voters, according to the national exit poll, a share that will only grow each election. Like other groups, Latino voters care most about jobs and the economy, but 35 percent of them listed immigration reform as their top issue in a poll conducted by Latino Decisions.

Latino voter and advocacy groups have said they expect both Obama and congressional Republicans to work together to pass immigration reform in 2013.

Eliseo Medina, secretary-treasurer of the Service Employees International Union, told reporters that Latino voters had sent a message to Obama. "We expect leadership on comprehensive immigration reform in 2013," he said. "To both sides we say: 'No more excuses.'"

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China opens power transfer by keeping it off-stage

BEIJING (AP) — China's ruling communists opened a pivotal congress to initiate a power handover to new leaders Thursday with a nod to their revolutionary past and a broad promise of cleaner government while keeping off-stage the main event — the bargaining over seats in the new leadership.

All the main players were arrayed on the stage in the Great Hall of the People: President Hu Jintao, his successor Xi Jinping and a collection of retired party insiders. A golden hammer and sickle, the Communist Party's symbol, hung on the back wall. Yet in a nearly two-hour opening ceremony, scant mention was made of the transition or that in a week Hu will step down as party chief in favor of Xi in what would be only the second orderly transfer of power in 63 years of communist rule.

The congress is writ small the state of Chinese politics today. It's a largely ceremonial gathering of 2,200-plus delegates who meet while the real deal-making is done behind-the-scenes by the true power-holders.

The centerpiece event of the opening of the weeklong congress — a 90-minute speech by Hu — served politics, allowing him to define his legacy after a decade in office, while marshaling his clout to install his allies in the collective leadership that Xi will head.

"An important thing for him is to make sure that there's no critical, no negative summary judgment of the past 10 years," said Ding Xueliang, a Chinese politics expert at Hong Kong University of Science and Technology. Still, Ding said, "90 percent of the effort is on putting your people in place."

The party's public silence on a leadership transition that everyone knows is taking place and that politically minded Chinese have been talking about has deepened a palpable sense of public unease. Many Chinese feel the country is at a turning point, in need of new ideas to deal with a slowing economy, growing piles of debt and rising public demands for more accountable, transparent government, if not democracy.

In signs of the public disquiet, at least four ethnic Tibetans in western China set themselves on fire on the eve of the congress in protests against Chinese rule of Tibetan areas, according to overseas Tibet support groups and the Tibetan government-in-exile in India.

At dawn in Tiananmen Square, next to the congress venue, a woman in her 30s threw pieces of torn paper into the air and shouted "bandits and robbers!" — a curse often leveled at corrupt local officials. She was taken away by the security forces, which have smothered all of Beijing for the congress.

In his speech, Hu cited many of the challenges China faces — a rich-poor gap, environmentally ruinous growth and imbalanced development between prosperous cities and a struggling countryside. Yet he offered little fresh thinking to address them and said restoring a relatively high growth would be the best way to deal with public expectations.

Only on tackling rampant corruption did Hu sound the alarm. He called on party members to be ethical and rein in their family members whose often showy displays of wealth have stoked public anger.

"Nobody is above the law," Hu said to the applause of the 2,309 delegates and invited guests, with Xi and other party notables on the dais behind him. He later said, "If we fail to handle this issue well, it could prove fatal to the party, and even cause the collapse of the party and the fall of the state."

Always an occasion for divisive bargaining, the leadership transition has been made more fraught by scandals that have fueled already high public cynicism that Chinese leaders are more concerned with power and wealth than government.

In recent months, one top leader, Bo Xilai, has been purged after his wife murdered a British businessman; a top aide to Hu was sidelined after his son crashed a Ferrari he shouldn't have been able to afford and foreign media reported that relatives of Xi and outgoing Premier Wen Jiabao had traded on their proximity to power to amass vast fortunes.

Public image aside, the scandals have especially weakened Hu, on whose watch they occurred, in the power-broking over the next leadership. In recent decades, the leadership line-ups have sought to balance different factions within the party. Who has prevailed won't be apparent until next Thursday, a day after the congress, when the members of the Politburo Standing Committee appear before the media.

On stage with Hu appeared one of his nemeses, his predecessor Jiang Zemin, who has supported Xi and is angling to fill many of the seats in the leadership with his allies. Nearby, dressed in a Mao jacket, sat 95-year-old Song Ping, a veteran of the revolution and party insider who was Hu's earliest political mentor.

Hu drew the line on political reform, a catchphrase for everything from greater transparency to democracy, even though retired party members, media commentators and government think tanks have in recent months called it an urgent need.

Hu's signature policy — a grab-bag of ideas meant to promote more balanced growth and stronger party rule that goes under the clunky phrase "the Scientific Outlook on Development" — has already been adopted in the party constitution. Hu's report to the congress called it "a powerful theoretical weapon" to guide the party.

"Even though this congress is about rejuvenation, passing the power to the young, what we see is the opposite," said Willy Lam of Chinese University of Hong Kong.

___

Associated Press writers Gillian Wong, Christopher Bodeen, Didi Tang and Louise Watt contributed to this report.

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Exclusive: Google Ventures beefs up fund size to $300 million a year

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